Cardiac Research
Breakthrough Discoveries in Pediatric Cardiovascular Medicine
Cardiac research at ¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾«Æ· Children’s is focused on improving care for children with heart conditions across every stage of life, from prenatal diagnosis to long-term recovery. Our teams are finding safer ways to perform surgery, supporting children with heart failure and transplants, and working to prevent heart disease before it starts.
Across our system, researchers, cardiologists, surgeons, psychologists, and imaging experts work to solve the most pressing challenges in pediatric cardiology. Our teams study how children’s hearts develop, adapt and respond to treatment, and how to support a child’s development and emotional well-being along the way.
Key Areas of ResearchÌý

Congenital Heart Disease & Surgery | UsingÌý3D modeling, advanced imaging, and outcomes data to plan safer surgeries and improve long-term results.
Fetal & Perinatal Cardiology | Advancing fetal imaging and prenatal counseling to detect and prepare for heart conditions before birth.
Heart Failure, Transplant & Recovery |ÌýStudying transplant outcomes, VADs, and recovery strategies to help children with advanced heart failure thrive.
Cardiac Neurodevelopmental Health | ExaminingÌýhow heart conditions affect learning, behavior, and emotions, and creating tools to support families along the way.
Prevention & Cardiovascular Genetics | StudyingÌýhow genetic and environmental factors contribute to heart conditions, and researching ways to reduce lifelong risk.
Clinical Trials & Research Studies
Our cardiac researchers lead and collaborate on clinical trials that explore innovative ways to care for children with heart disease. These studies cover a wide range of topics, including surgery, transplant, imaging, mental health, and prevention.
We partner with national research networks such as the Pediatric Heart Network, the Pediatric Cardiac Critical Care Consortium (PC4), and the Patient-Centered Outcomes Research Institute (PCORI) to bring promising innovations to children and families sooner.

Where Cardiac Research Happens at ¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾«Æ·
Cardiac research at ¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾«Æ· is anchored by a dedicated center in the Delaware Valley and robust research services in Florida. We have a growing network of basic and translational labs, clinical collaborators, and national research partnerships. Researchers work hard to bring discoveries directly into care for children with heart disease.
Related Research
Cardiovascular Services Department Research, Florida
FLORIDA
Our researchers use imaging, data analysis, and molecular research to develop new approaches to prevent, diagnose, and treat congenital and acquired heart conditions in children.
¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾«Æ· Cardiac, Center for Research & Innovation
DELAWARE VALLEY
We study the impact of innovations, access, and health care delivery on outcomes in heart surgery, preventive cardiology, and more.
Cardiac Clinical Care
Cardiac Center, Delaware Valley
CLINICAL CARE
Pediatric cardiology, heart surgery and transplantation at ¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾«Æ· Children’s Hospital, Delaware and throughout Greater Philadelphia.
Cardiac Center, Florida
CLINICAL CARE
Pediatric cardiology and specialty care at ¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾«Æ· Children’s Hospital, Florida and throughout Northeast, Northwest, and Central Florida.