Cancer & Blood Disorder Clinical Trials
What We’re Studying Now
At ¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾Ã¾«Æ· Children’s, our clinical trials in hematology and oncology aim to improve survival, reduce side effects, and support every stage of treatment for children, teens, and young adults.
We’re studying brain and solid tumors, blood cancers, transplant outcomes, and the long-term impact of treatment. We aim to find safer, more effective care.
Blood Cancers (Leukemia & Lymphoma)
Brain & Central Nervous System Tumors
Effects of Carboplatin and Isotretinoin on Participants With High Risk Medulloblastoma
DELAWARE VALLEY & NORTHWEST FLORIDA
Reduced Dose Craniospinal Radiotherapy in Children With Medulloblastoma
DELAWARE VALLEY & NORTHWEST FLORIDA
Study of Irinotecan and Bevacizumab With Temozolomide in Children With Central Nervous System Tumors
NORTHEAST FLORIDA
Trial of Lenalidomide in Patients With Juvenile Pilocytic Astrocytomas & Optic Pathway Gliomas
DELAWARE VALLEY & NORTHWEST FLORIDA
Trial of Modafinil to Improve Neurocognitive Deficits in Children Treated for a Primary Brain Tumor
DELAWARE VALLEY & NORTHWEST FLORIDA
Trial of Postradiation Chemotherapy in Patients With Newly Diagnosed Ependymoma
DELAWARE VALLEY & NORTHWEST FLORIDA
Solid Tumors
A Trial of Multimodality Therapy for Extra-Ocular Retinoblastoma
DELAWARE VALLEY
Dose Escalation of Metformin With Standard Chemotherapy Drugs in Children With Solid Tumors
DELAWARE VALLEY & NORTHEAST FLORIDA
Irinotecan/Temozolomide Antibody in Children With Refractory, Relapsed or Progressive Neuroblastoma
DELAWARE VALLEY & NORTHEAST FLORIDA
National Wilms Tumor Late Effects Study
DELAWARE VALLEY, NORTHEAST FLORIDA & CENTRAL FLORIDA
Treatment for Ewing Sarcoma Adding Topotecan to Chemotherapy
DELAWARE VALLEY & NORTHWEST FLORIDA
Transplant & Supportive Therapies
Caspofungin vs. Fluconazole to Prevent Invasive Fungal Infections in Children in Chemotherapy
DELAWARE VALLEY & NORTHWEST FLORIDA
Rescue Immunotolerance Study in Immunotolerance Induction Naive Patients (RESIST)
NORTHEAST FLORIDA
Safety of LactoBacillus Platarum in Children Undergoing Allogeneic HSCT
NORTHEAST FLORIDA
More About Clinical Trials
Learn what clinical trials involve and what to consider when deciding if participation is a good fit for your family.
How Research Connects to Care
Our hematology and oncology research drives new discoveries in how we diagnose, treat, and support children with cancer and blood disorders.
From new therapies to long-term follow-up, our studies help improve survival and quality of life for young patients and their families.